ПИЛОТНАЯ IN VIVO ВЕРИФИКАЦИЯ  ВОЛОКОННО-ОПТИЧЕСКОГО СЕНСОРА

Глеб Егорович Соболев; Алия Алмазовна Камалеева; Алсу Айратовна Сахабутдинова; Никита Дмитриевич Смирнов; Булат Ильгизярович Валеев; Тимур Артурович Аглиуллин

Глеб Егорович Соболев Kazan (Volga Region) Federal University, Institute of Physics http://orcid.org/0009-0004-5036-570X
Алия Алмазовна Камалеева Kazan National Research Technical University named after A.N.Tupolev-KAI http://orcid.org/0009-0005-4206-463X
Алсу Айратовна Сахабутдинова MAOU "Lyceum - Engineering Center" http://orcid.org/0000-0002-0332-1163
Никита Дмитриевич Смирнов Kazan National Research Technical University named after A.N.Tupolev-KAI http://orcid.org/0009-0002-7372-4053
Булат Ильгизярович Валеев Kazan National Research Technical University named after A.N.Tupolev-KAI http://orcid.org/0000-0002-1643-4183
Тимур Артурович Аглиуллин Kazan National Research Technical University named after A.N.Tupolev-KAI http://orcid.org/0000-0003-1043-7487

Keywords: fiber-optic sensor; fiber Bragg grating; in vivo; spectral signal processing; intracerebral implantation.

Abstract

An in vivo verification of a fiber-optic sensor based on a fiber Bragg grating formed near the tip of a single-mode optical fiber and implanted into mouse brain tissue is reported. Optimization of the sensing element geometry enabled the registration of a physiologically modulated optical signal. Spectral analysis of the recorded response revealed a stable component in the frequency range associated with the respiratory rhythm of the anesthetized animal. The detected signal may contain both physiological and mechanical contributions, and its interpretation is complicated by the presence of a Fabry–Perot-type interference component. The findings demonstrate the feasibility of the proposed approach and support its further development for in vivo applications.

Author Biographies

Глеб Егорович Соболев, Kazan (Volga Region) Federal University, Institute of Physics

Physics student at Kazan (Volga Region) Federal University.

ORCID: 0009-0004-5036-570X.

Алия Алмазовна Камалеева, Kazan National Research Technical University named after A.N.Tupolev-KAI

Student in the Department of Radiophotonics and Microwave Technologies at the Kazan National Research University named after A.N. Tupolev-KAI.

Research interests: fiber-optic sensors in medicine, biosensors, and quantum technologies.

ORCID: 009-0005-4206-463X

Алсу Айратовна Сахабутдинова, MAOU "Lyceum - Engineering Center"

Student at the Municipal Autonomous General Education Institution "Lyceum-Engineering Center" in the Sovetsky District of Kazan.

Research interests: biology and optics.

ORCID: 0000-0002-0332-1163.

Никита Дмитриевич Смирнов, Kazan National Research Technical University named after A.N.Tupolev-KAI

Postgraduate student in the Department of Radiophotonics and Microwave Technologies at the Kazan National Research Technical University named after A.N. Tupolev-KAI.

Research interests: fiber optics, fiber-optic sensors.

ORCID: 0009-0002-7372-4053

Булат Ильгизярович Валеев, Kazan National Research Technical University named after A.N.Tupolev-KAI

Postgraduate student in the Department of Radiophotonics and Microwave Technologies at the Kazan Aviation Technical University named after A.N. Tupolev-KAI.

Research interests: Mathematical modeling, combined fiber-optic structures, fiber-optic measurement systems, radiophotonic interrogation, artificial neural networks.

ORCID: 0000-0002-1643-4183

Тимур Артурович Аглиуллин, Kazan National Research Technical University named after A.N.Tupolev-KAI

Candidate of Engineering Sciences, Associate Professor, Associate Professor of the Department of Radiophotonics and Microwave Technologies at KNITU-KAI.

Research interests: fiber-optic sensors.

ORCID: 0000-0003-1043-7487.

PILOT IN VIVO VERIFICATION OF A FIBER-OPTIC SENSOR

Abstract

Author Biographies